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They target HDAC1/2 to rebalance epigenetics, modulate NF-B (Figure 3), and reduce cytokines such as TNF-, IL-1, and IL-6, along with MMPs

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If PPGs indicate a need for improvement of glycemic control, clinicians can consider either a GLP-1 RA (for T2D) or bolus insulin (T1D or T2D)

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